Nevada boxing regulators say Manny Pacquiao and Timothy Bradley will be subject to stepped-up drug and hormone testing before their April 12 rematch in Las Vegas.

Nevada Athletic Commission Chairman Francisco Aguilar said Friday the two welterweights will face unannounced pre-fight testing handled by collectors certified by the World Anti-Doping Agency.

Plans call for samples to undergo isotope-ratio mass spectrometry to detect exogenous testosterone from outside the body.

Aguilar called enhanced pre-fight testing a new normal for boxing and mixed martial-arts.

He credited Top Rank promoter Bob Arum with supporting the testing protocol.

Bradley (31-0, 12 KOs) and Pacquiao (55-5-2, 38 KOs) will be fighting for the WBO 147-pound title at the MGM Grand Garden arena.

Bradley won a controversial split decision over Pacquiao in June 2012 in Las Vegas.