US President Donald Trump says “it’s possible” America may get involved in the conflict between Iran and Israel.

“We’re not involved in it. It’s possible we could get involved. But we are not at this moment involved,” Trump told the US’s ABC News late on Sunday (US time).

The network has also reported that Trump expressed interest in the possibility of Russian President Vladimir Putin mediating in the conflict.

“I would be open to it. [Putin] is ready. He called me about it. We had a long talk about it. We talked about this more than his situation. This is something I believe is going to get resolved,” Trump said.

Earlier, before he left for the Group of Seven summit in Canada, Trump was asked what he was doing to de-escalate the situation.

“I hope there’s going to be a deal. I think it’s time for a deal,” he said.

“Sometimes they have to fight it out. We’ll see what happens.”

However, he would not say if he had asked Israel to halt its strikes on Iran.

“I don’t want to say that,” he said.

Elsewhere, two US officials have told Reuters that Trump vetoed an Israeli plan in recent days to kill Iran’s Supreme Leader Ayatollah Ali Khamenei.

“There’s so many false reports of conversations that never happened, and I’m not going to get into that,” Israeli Prime Minister Benjamin Netanyahu told Fox News of the report on Sunday.

“We do what we need to do,” he told Fox’s Special Report With Bret Baier.

Iranian missiles struck Israel’s Tel Aviv and the port city of Haifa late on Sunday (local time), destroying homes and fuelling concerns among world leaders at this week’s G7 meeting that the battle between the bitter enemies could lead to a broader regional conflict.

Israeli media reported that three people were killed in the country’s centre on Monday while dozens more were wounded in overnight strikes.

Search and location operations were under way in the northern city of Haifa where about 30 people were wounded, emergency authorities said, as dozens of first responders rushed to the strike zones.

Fires were burning at a power plant near the port, media reported.

The Israel Defence Forces said on X hundreds of people had been forced to shelter because of Iranian ballistic missiles.

Live video footage also showed missiles over Tel Aviv and explosions could be heard there and over Jerusalem. Residential buildings in Tel Aviv had been struck, Reuters witnesses said.

Tehran has launched waves of attacks on Israel in retaliation for Israel’s pre-emptive strikes targeting Iran’s nuclear and ballistic missile programs that began on Friday.

Iran’s Revolutionary Guards said the latest attack employed a method that caused Israel’s multilayered defence systems to target each other.

“The initiatives and capabilities used in this operation, despite the comprehensive support of the United States and Western powers and the possession of the most up-to-date and newest defence technology, led to the successful and maximum hitting of the missiles on the targets in the occupied territories,” it said.

At least 10 people in Israel, including children, were killed in earlier strikes, authorities said.

Iran has told mediators Qatar and Oman that it is not open to negotiating a ceasefire while it is under Israeli attack, an official briefed on the communications told Reuters on Sunday.

Israel began its assault with a surprise attack on Friday that wiped out the top echelon of Iran’s military command and damaged its nuclear sites, and says the campaign will escalate in coming days.

The intelligence chief of Iran’s Revolutionary Guards, Mohammad Kazemi, and his deputy were killed in attacks on Tehran on Sunday, Iran’s semi-official Tasnim news agency said.

Iran has vowed to “open the gates of hell” in retaliation.

Trump has lauded Israel’s offensive while denying Iranian allegations that the US has taken part and warning Tehran not to widen its retaliation to include US targets.

Two US officials said on Friday the US military had helped shoot down Iranian missiles that were headed toward Israel.

Trump has repeatedly said Iran could end the war by agreeing to tough restrictions on its nuclear program. Iran maintains it is for peaceful purposes but which Western nations and the IAEA nuclear watchdog say it could be used to make an atomic bomb.

-with AAP