A vehicle laden with explosions has exploded in the Turkish capital of Ankara at rush hour, killing at least 28 people.

The car bomb detonated on Thursday morning (AEDT) near Turkish military headquarters, parliament and government buildings. The sound of the blast was reportedly heard across the city.

Both the Islamic State and the outlawed Kurdistan Workers Party (PKK) were blamed. Neither group has claimed responsibility.

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The bomb was detonated in Ankara’s administrative centre, near parliament. Photo: Getty

A further 40 people were injured by the blast, which Justice Minister Bekir Bozdag described as an “act of terrorism” on Twitter.

Ankara governor Mehmet Kiliçer told media the explosion was aimed at a convoy of army vehicles passing through the capital’s administrative centre.

“I heard a huge explosion. There was smoke and a really strong smell even though we were blocks away,” a witness told Reuters. “We could immediately hear ambulance and police car sirens rushing to the scene.”

The attack followed a suicide bombing in Istanbul in January 2016, a double suicide bombing in October 2015 that killed 103 people, and another suicide bombing in Suruc in July 2015.

The Turkish government is fighting Islamic State militants on the Turkey-Syria border as well as a decades-old war for independence with Kurds, a minority ethnic group.

Prime Minister Ahmet Davutoğlu cancelled a trip to Brussels after the attack.

-with AAP