A motorcyclist has died after a brief police pursuit in suburban Perth.

WA Police’s major crash squad and internal affairs are investigating Saturday’s fatal crash in Hillarys, north of Perth.

A police spokesman said a man on a Ducati motorcycle approached a booze bus on West Coast Drive about 8.40pm (WST) but failed to stop for a breath test.

In the ensuing pursuit, the motorcyclist sped onto nearby Hepburn Avenue, where he slammed into a BMW being driven in the opposite direction.

The 28-year-old rider from Beldon was seriously injured and died at the scene.