Police have raided a number of premises across Victoria linked to the Comancheros outlaw motorcycle gang, with 60 warrants being executed across the state.

Police blocked off Thistlethwaite Street in South Melbourne while they searched a property linked to the Comancheros outlaw motorcycle gang.

Police from the Echo Taskforce have been inside with detectives and have emerged with brown paper bags.

It is unclear if anyone has been arrested.

Police are in the process of executing a large number of warrants across the state at clubhouses and homes of Comancheros and their associates.