Three people have been taken to hospital after an apparent minor chemical explosion in inner Sydney.

Fire and Rescue NSW said its officers arrived at the University of Sydney Sports Aquatic Centre in Darlington about 10am on Tuesday after reports of a person suffering from chemical burns.

One employee and two bystanders were affected by the acid-based chemicals, which were being moved for disposal.

One of those involved received burns to his hands.

He has been taken to Royal Prince Alfred hospital, after “exposure to the vapour cloud that came off the reaction” inside a plastic bucket, FRNSW said.

The other two people involved were also taken to hospital as a precaution.

Firefighters set up an exclusion zone and called for a specialist HAZMAT crew to assist.

Crews worked to decontaminate areas where people had washed off after the chemical flash – described as a “rapid release of heat”.

The university said an exclusion zone had been set up.

“All members of our community are asked to please avoid the area around Codrington Street and Butlin Avenue until further notice,” it said.

The university’s services building was evacuated as a precaution, but there were no other disruptions to daily activities.

“We’re grateful there do not seem to have been serious injuries as a result. However, ambulance services are on campus and providing appropriate health care to the small number we’re aware of who require it,” the university said.

“If you were in the vicinity of the G09 and G12 locations this morning, are suffering from any of the following symptoms, or think you were exposed to any chemicals, please seek immediate medical advice: Itchiness to skin/eyes and irritation to respiratory tract.”

SafeWork and the NSW Environment Protection Authority have been informed of the incident.

There is no ongoing safety risk to the community.