A 39 year-old Sydney woman has been arrested and charged for allegedly fraudulently taking more than $2 million from a number of men aged in their 60s and 70s, police say.

It is alleged the single mother of four from Miller in southwest Sydney used dating services for about five years, from mid-2008 to February this year, to form relationships with four different men.

Two of the men are aged in their 70s, while the other two are in their 60s, police say.

One of the men allegedly paid the woman $1.9 million.

The other three men paid her $190,000, $58,000, and $12,000 respectively.

After making contact with the men, police say the woman would convince them to deposit money into her account, sometimes claiming she needed money to care for a sick relative.

The woman was arrested on Thursday and police seized several items including a sports car.

The woman has been charged with several counts of fraud and money laundering.

She was granted bail and will appear in Liverpool Local Court on June 25.