A 15-year-old Melbourne teenager with five passengers squeezed into his car has been nabbed doing 220km/h.

Officers began chasing the Holden Commodore when the front-seat passenger hung out of the window and yelled abuse as the sedan passed the stationary police vehicle.

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Police followed the Holden as it accelerated sharply and intercepted it travelling at 220km/h in an 80kmh zone in Mulgrave after 2.15am.

Police found six males in the car, aged between 15 and 17. The four in the back seat were not wearing seat belts.

The driver, a 15-year-old from Hampton Park, has been released pending summons.

He will be interviewed for excessive speed, conduct endangering life, unlicensed driving and other traffic-related offences.

The vehicle was impounded for 30 days; the owner will have to pay $733 to get it back.