A man has died after being stabbed in the chest in Sydney’s northwest.

The 28-year-old was found in a critical condition at Narcissus Avenue in Quakers Hill about 8.30pm on Friday.

Paramedics worked to save the man but he died en route to hospital.

Detectives probing the incident have asked anyone with CCTV footage, dashcam or information about what happened to come forward.

A crime scene has been set up at the residential street.

-AAP