Police are investigating after a man was shot in the head and chest in a south-western Sydney carpark, and a car crashed into a house and caught fire.

The 27-year-old man was peppered in bullets in the shooting on Canterbury Road, Campsie, on Tuesday night.

Police were called to the scene about 9.20pm. The man was treated by paramedics before being taken to St George Hospital in a serious condition.

Sydney media report the shooting is believed to be linked to the city’s underworld wars.

A short time later emergency services were called to Kingsgrove, where a Mercedes sedan had crashed into a house before catching alight.

No injuries were reported at the house fire on Kilkee Avenue, and the fire was extinguished by Fire and Rescue NSW.

Police are investigating three burnt-out cars found soon after the shooting. Photo: 7NEWS

There are reports that police are also investigating possible links to two other burnt-out cars discovered on Tuesday night.

Crime scenes were established at both scenes and detectives have begun an investigation.

Police have urged anyone with CCTV, dashcam footage or information about either incidents to contact Burwood police or Crime Stoppers on 1800 333 000.