Beverly Hills, 90210 star Shannen Doherty has shared a heartbreaking update on her cancer, revealing the disease has spread to her bones.

The 52-year-old actress was diagnosed with breast cancer in 2015.

Thursday’s update comes only months after the Charmed star revealed the cancer had spread to her brain – and she had previously had surgery to remove a tumour she had dubbed Bob.

“He had to get removed and dissected to see his pathology,” she said at the time. “It was definitely one of the scariest things I’ve ever been through in my entire life.”

On Thursday, Doherty said her stage four cancer had metastasized to her bones.

“I don’t want to die,” she told People magazine on Thursday (AEDT).

“I’m not done with living. I’m not done with loving. I’m not done with creating. I’m not done with hopefully changing things for the better. I’m just not – I’m not done.”

Stage four cancer means the disease has spread to other parts of the body, such as the bones, liver, lungs, or brain.

Doherty’s breast cancer was initially revealed in a lawsuit that she and then-husband Kurt Iswarienko filed against her former accountants and business managers.

After rounds of chemotherapy, radiotherapy and surgery, she announced she was in remission in April 2017.

However, the cancer returned in 2019, unbeknown to many of Doherty’s colleagues. She kept filming with her Beverly Hills castmates to reprise her role as Brenda Walsh in the series reboot, even while she had treatment.

She told People this week that cancer patients were “vibrant, and we have such a different outlook on life”.

“We’re just so grateful for every second, every hour, every day that we get to be here. We are people who want to work and embrace life and keep moving forward,” Doherty said.

But she admitted her diagnosis had led her to look for a “bigger purpose”, like raising awareness and funds for cancer research.

“When you ask yourself, ‘Why me? Why did I get cancer?’ and then ‘Why did my cancer come back? Why am I stage four?’ that leads you to look for the bigger purpose in life,” she said.

“It’s insane to me [that] we still don’t have a cure.”

Doherty, who has had a mastectomy, has previously expressed her gratitude for her medical team at Los Angeles’ Cedars-Sinai. But she also revealed her “fear” of her cancer battle.

“The turmoil….. the timing of it all,” she said. “This is what cancer can look like.”

This week, she told People that she hoped to be admitted into clinical trials and was driven to prove that she could still work despite her illness.

“People don’t know a lot about cancer,” she said.

“I think they just sort of assume that it means you can’t walk, you can’t eat, you can’t work. People put you out to pasture at a very early age – ‘You’re done. You’re retired’ – and we’re not.”

Doherty will discuss more about her diagnosis on her memoir podcast, Let’s Be Clear with Shannen Doherty. It is released on December 6.